|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Currently, many researches indicated that PAK5 was dysregulated in ovarian cancer, cervical cancer, melanoma, osteosarcoma, renal carcinoma, breast cancer, gastric cancer and so on, which was involved in cell proliferation, apoptosis, migration and invasion.
|
31805288 |
2020 |
|
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis.
|
31219614 |
2020 |
|
Malignant Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
This review focuses the latest knowledge on the structure, expression, signalling pathway of PAK5, emphasizing its function in cancer.
|
31805288 |
2020 |
|
Primary malignant neoplasm
|
0.050 |
AlteredExpression
|
group |
BEFREE |
This review focuses the latest knowledge on the structure, expression, signalling pathway of PAK5, emphasizing its function in cancer.
|
31805288 |
2020 |
|
Malignant neoplasm of breast
|
0.040 |
Biomarker
|
disease |
BEFREE |
These findings suggest a pivotal role for PAK5-elicited signaling in breast cancer progression.
|
31219614 |
2020 |
|
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
These findings suggest a pivotal role for PAK5-elicited signaling in breast cancer progression.
|
31219614 |
2020 |
|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
PAK5 promotes the migration and invasion of cervical cancer cells by phosphorylating SATB1.
|
30082769 |
2019 |
|
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Taken together, we conclude that PAK5 is a novel prognostic indicator and plays an important role in the CC metastasis.
|
30082769 |
2019 |
|
Malignant Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
p21-activated kinase 5 (PAK5) is involved in several oncogenic signaling pathways and its amplification or overexpression has been found in various types of cancer; however, the pathophysiologic role of PAK5 in cervical cancer (CC) remains elusive.
|
30082769 |
2019 |
|
Primary malignant neoplasm
|
0.050 |
Biomarker
|
group |
BEFREE |
p21-activated kinase 5 (PAK5) is involved in several oncogenic signaling pathways and its amplification or overexpression has been found in various types of cancer; however, the pathophysiologic role of PAK5 in cervical cancer (CC) remains elusive.
|
30082769 |
2019 |
|
Glioma
|
0.020 |
Biomarker
|
disease |
BEFREE |
These results indicated that miR‑489 may be involved in PAK5‑mediated regulation of glioma progression, demonstrating the potential therapeutic benefits of targeting miR‑489 in glioma.
|
31638257 |
2019 |
|
Secondary malignant neoplasm of lung
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, overexpression of PAK5 induced lung metastasis of CC cells in xenograft modes.
|
30082769 |
2019 |
|
Malignant tumor of cervix
|
0.010 |
Biomarker
|
disease |
BEFREE |
Taken together, we conclude that PAK5 is a novel prognostic indicator and plays an important role in the CC metastasis.
|
30082769 |
2019 |
|
Cervix carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Taken together, we conclude that PAK5 is a novel prognostic indicator and plays an important role in the CC metastasis.
|
30082769 |
2019 |
|
cervical cancer
|
0.010 |
Biomarker
|
disease |
BEFREE |
Taken together, we conclude that PAK5 is a novel prognostic indicator and plays an important role in the CC metastasis.
|
30082769 |
2019 |
|
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
Tumor Cell Invasion
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer.
|
30245957 |
2018 |
|
Neoplasm Metastasis
|
0.070 |
AlteredExpression
|
phenotype |
BEFREE |
PAK5 expression was identified to be significantly associated with metastasis (P=0.010).
|
29434926 |
2018 |
|
Neoplasm Metastasis
|
0.070 |
AlteredExpression
|
phenotype |
BEFREE |
It was initially found that PAK5 was highly expressed in ovarian cancer tissues, particularly in patients with distant metastasis.
|
30245957 |
2018 |
|
Malignant neoplasm of breast
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
<b>Results:</b> PAK7 expression was significantly increased in breast cancer tissues and positively correlated with pathological differentiation and TNM stage of breast cancer.
|
29805709 |
2018 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Tumor tissues were taken from the osteosarcoma patients with chemotherapy resistance to detect the expression levels of PAK5 and Ezrin via immunohistochemical detection, and the correlation between PAK5 and Ezrin expressions was studied.
|
29391894 |
2018 |
|
Breast Carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
<b>Results:</b> PAK7 expression was significantly increased in breast cancer tissues and positively correlated with pathological differentiation and TNM stage of breast cancer.
|
29805709 |
2018 |
|
Osteosarcoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Tumor tissues were taken from the osteosarcoma patients with chemotherapy resistance to detect the expression levels of PAK5 and Ezrin via immunohistochemical detection, and the correlation between PAK5 and Ezrin expressions was studied.
|
29391894 |
2018 |
|
Osteosarcoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
PAK5 overexpression is associated with lung metastasis in osteosarcoma.
|
29434926 |
2018 |
|
Osteosarcoma of bone
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
PAK5 overexpression is associated with lung metastasis in osteosarcoma.
|
29434926 |
2018 |